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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
21.52
Human Site:
S96
Identified Species:
36.41
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
S96
A
L
L
E
K
N
R
S
Y
R
L
L
E
D
S
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S96
A
L
L
E
K
N
R
S
Y
R
L
L
E
D
S
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
S96
A
L
L
E
K
N
R
S
Y
R
L
L
E
D
S
Dog
Lupus familis
XP_538827
1042
119346
S96
A
L
L
E
K
N
R
S
Y
K
L
L
E
D
S
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
D135
P
S
A
R
T
M
L
D
E
E
D
V
K
V
A
Rat
Rattus norvegicus
NP_997661
1044
119245
S96
A
L
L
E
K
N
R
S
Y
K
L
L
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
D99
L
G
I
S
H
A
R
D
K
L
V
Y
I
H
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
T93
E
M
E
R
K
N
R
T
Y
T
L
L
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
L68
I
E
E
A
T
K
R
L
K
L
E
H
E
D
R
Honey Bee
Apis mellifera
XP_001122325
831
95330
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
L88
A
E
L
A
E
Q
E
L
N
R
L
N
R
A
V
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
K96
E
G
D
D
Q
K
F
K
G
L
A
I
K
D
T
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
I135
T
I
F
K
I
Y
Q
I
A
S
P
P
V
M
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
N.A.
6.6
N.A.
60
N.A.
20
0
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
N.A.
26.6
N.A.
73.3
N.A.
20
0
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
8
15
0
8
0
0
8
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
15
0
0
8
0
0
58
0
% D
% Glu:
15
15
15
36
8
0
8
0
8
8
8
0
50
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
8
8
8
0
8
0
0
8
0
0
0
8
8
0
0
% I
% Lys:
0
0
0
8
43
15
0
8
15
15
0
0
15
0
8
% K
% Leu:
8
36
43
0
0
0
8
15
0
22
50
43
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
43
0
0
8
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
0
0
58
0
0
29
0
0
8
0
8
% R
% Ser:
0
8
0
8
0
0
0
36
0
8
0
0
0
0
43
% S
% Thr:
8
0
0
0
15
0
0
8
0
8
0
0
0
0
15
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
43
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _